Evaluation of Anti Infl Ammatory Activity of Fruits Extract of Sterculia Lychnophora

Abstract

Indian herbal therapy is assessed using the vast body of research on herbal plant species and their therapeutic principles conducted worldwide. In both conventional and modern medicine, medicinal plants that are shown to contain effective bioactive chemicals are used. For a variety of causes, a large proportion of patients experience rheumatoid arthritis with unknown inflammation. Therefore, the assessment of the anti-inflammatory properties of Sterculia lychnophora fruits is the focus of this study. The plant's fruits were gathered, removed, and put through both qualitative and quantitative testing. Additionally, the in vivo anti-inflammatory efficacy was examined in a model of paw edoema caused by carrageen. The results of the phytochemical testing indicated the presence of phenol, steroids, alkaloids, glycosides, tannins, and flavonoids. It was discovered that the total phenol and flavonoid content was, respectively, 0.857 mg/100 mg and 0.922 mg/100 mg. After 4 hours, the paw edoema in 100 mg/kg and 200 mg/mg was 2.75±0.32 & 1.23±0.20, respectively. When using the regular medication indomethacin, the paw edoema volume at the end of the fourth hour was 1.05±0.15.  Therefore, it can be said that the extract's anti-inflammatory potential is almost as great as that of a prescription medication.